Baclofen therapy for chronic hiccup

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Baclofen therapy for chronic hiccup.

Chronic hiccup is a rare but potentially severe condition, that can be symptomatic of a variety of diseases, or idiopathic. Many therapeutic interventions have been reported, most often as case reports. Among other drugs, baclofen has been suggested as a therapy for chronic hiccup. In a large series of patients, we have evaluated its therapeutic position. In patients with chronic hiccup, define...

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Successful treatment of chronic hiccup with baclofen in cancer patients.

Chronic hiccup is an infrequent but distressing symptom in patients with advanced cancer. A series of drugs (chlorpromazine, haloperidol, nifedipine, metoclopramide, baclofen) have been used to treat hiccup without definitive results. Some authors have suggested a possible role of baclofen in the treatment of chronic hiccup. We report three cases of chronic hiccup in patients with cancer succes...

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[Intrathecal baclofen therapy for hereditary spastic paraplegia].

Intrathecal baclofen therapy (ITB) is an established treatment for intractable spasticity. More than 1,100 patients have undergone ITB in Japan, and there are about 50 hereditary spastic paraplegia (HSP) The features of ITB in HSP are 1. small doses of baclofen may often be enough, 2. small changes of doses later the symptoms remarkably, 3. doses can be decreased after long term ITB.

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Revisiting Baclofen for the Treatment of Severe Chronic Tinnitus

tinnitus to begin with. Another was that the study was potentially underpowered statistically due to the inclusion of several different types of tinnitus, some of which might not have responded to the drug (Møller, 1997). The possibility that the study was underpowered was carefully acknowledged by the authors themselves, who performed power calculations for different scenarios (Westerberg et a...

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Why do we hiccup?

Why do we hiccup? Considering the fact that almost everyone experiences hiccups at one time or another, remarkably little is known about them. The name itself is onomatopoeic, which is appropriate considering that the only common understanding of the hiccup is of the characteristic sound. Hiccups can be predictably elicited in some individuals by overindulgence of food, alcohol, or both, someti...

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ژورنال

عنوان ژورنال: European Respiratory Journal

سال: 1995

ISSN: 0000-0000,0903-1936

DOI: 10.1183/09031936.95.08020235